Mj. Reilly et al., OCULAR EFFECTS OF EXPOSURE TO TRIETHYLAMINE IN THE SAND CORE COLD BOXOF A FOUNDRY, Occupational and environmental medicine, 52(5), 1995, pp. 337-343
Objectives-To assess the acute and chronic ophthalmological effects of
triethylamine exposure among foundry workers. Methods-Ocular effects
on people currently, previously, and never exposed to triethylamine in
a foundry cold box were studied at two points in time. The initial ph
ase included an ocular examination with a slit lamp to assess corneal
health, a visual acuity test, and a questionnaire to assess vision sym
ptoms. The follow up included measurements of corneal thickness with a
n ultrasonic pachymeter and the vision symptoms questionnaire before a
nd after the shift and at the beginning and end of the week. Personal
air measurements for triethylamine were also obtained during the follo
w up. Results-The vision symptoms of blurriness, halos around lights,
and blue hazy vision occurred more often in currently exposed workers
than those previously or never exposed to triethylamine. Air concentra
tions of triethylamine ranged from < 0.33 mg/m(3) to 20.3 mg/m(3). Amo
ng currently exposed workers, symptoms were more common among those wi
th exposure to > 10 mg/m(3) of triethylamine (odds ratio (OR) = 3.0, 9
5% confidence interval (95% CI) 0.35-25.6). No differences in corneal
thickness were found in currently or previously exposed workers and th
ose never exposed. No increase in corneal thickness was found after up
silon before the shift. Conclusion-Despite low concentrations of triet
hylamine and no corneal oedema, workers exposed to triethylamine repor
ted vision symptoms. Possible explanations for these symptoms without
corneal oedema are that triethylamine affects ciliary muscle function
or that the corneal oedema was transient and not present when corneal
thickness measurements were taken. No chronic effects were found in pr
eviously exposed workers. Further research is needed to elucidate the
mechanism for the reported vision symptoms, which occurred below the c
urrent United States eight hour time weighted standard of 100 mg/m(3)
and the American Conference of Governmental Industrial Hygienists (ACG
IH) recommended value at the time of our study of 40 mg/m3. We recomme
nded that air concentrations be maintained to meet the current recomme
nded ACGIH threshold of 4.1 mg/m3.