S. Caron et al., SYNTHESIS OF 1-SUBSTITUTED AND 1,4-DISUBSTITUTED 2,3-DI-O-BENZYL-1,6-ANHYDROGALACTOFURANOSES, Journal of organic chemistry, 60(9), 1995, pp. 2780-2785
A method has been developed for synthesizing 1-substituted and 1,4-dis
ubstituted 2,3-di-O-benzyl-1,6-anhydrogalactofuranoses 16 starting fro
m 8, a known 1,6-anhydropyranose prepared from D-galactose. Compounds
such as 16 have potential utility for synthesis of the squalestatins a
nd zaragozic acids.