Basilar artery (BA) occlusion is generally believed to have a high mor
tality. A favorable outcome is rarely reported, A consecutive series o
f 20 survivors with angiographically proven symptomatic BA occlusion n
ot treated with thrombolysis or selected for outcome were analyzed for
clinical presentation and neuroradiologic features to find outcome pr
edictors. Long-term functional outcome (Rankin scale) was good in 12 (
60%), moderate in 4 (20%), and poor in 4 (20%) patients who had comple
te mid-segmental BA occlusions and bilateral large pontine infarcts. P
rominent retrograde collateral supply from the carotids and/or anterog
rade from the cerebellar arteries was present in all patients with ade
quate angiographic studies (n = 18). BA occlusion was proximal in 12,
mid-segmental in 7, and distal in 1 patient. Stroke etiology was consi
dered atherothrombotic in 14 (70%), embolic in 2 (10%), and related to
migraine in 4 (20%). Clinical outcome following BA occlusion is more
heterogenous than usually presumed and influenced by the temporal cour
se, length of BA occlusion, availability of collateral circulation, an
d extent of brainstem infarction. The etiology of benign BA occlusion
is mostly local thrombosis.