Ki. Keverline et al., SYNTHESIS OF THE 2-BETA,3-ALPHA-ISOMERS AND 2-BETA,3-BETA-ISOMERS OF 3-(P-SUBSTITUTED PHENYL)TROPANE-2-CARBOXYLIC ACID METHYL-ESTERS, Tetrahedron letters, 36(18), 1995, pp. 3099-3102
The synthesis of 3-(p-substituted phenyl)trop-2-ene-2-carboxylic acid
methyl ester 8 and its reduction with samarium iodide provide a new sy
nthesis of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic aci
d methyl ester (2) and, in addition, give the first synthesis of the 2
beta,3 alpha-diastereoisomer 4.