A NEW AND EFFICIENT PREPARATION OF ALPHA,BETA-DEHYDROAMINO ACIDS

Authors
GOODALL K PARSONS AF
Citation
K. Goodall et Af. Parsons, A NEW AND EFFICIENT PREPARATION OF ALPHA,BETA-DEHYDROAMINO ACIDS, Tetrahedron letters, 36(18), 1995, pp. 3259-3260
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
18
Year of publication
1995
Pages
3259 - 3260
Database
ISI
SICI code
0040-4039(1995)36:18<3259:ANAEPO>2.0.ZU;2-7
Abstract
A new one-pot synthesis of dehydroamino acids has been developed by re action of beta-hydroxy-alpha-amino acids with dichloroacetyl chloride and a tertiary amine base. The reaction proceeds in 58-89% yield.