Assembly of the broad-host-range bacteriophage PRD1 involves transloca
tion of the virus-specific membrane to the inside of the icosahedral p
rotein shell formed of trimeric coat proteins. The formation of PRD1 p
articles is, in addition to the virus-encoded assembly factors P10 and
P17, dependent on GroEL/GroES chaperonins. The chaperonins assist in
the folding of the capsid proteins P3 and P5 and in the assembly of vi
ral membrane proteins. (C) 1997 Academic Press