A VARIANT T(14-17) IN ACUTE PROMYELOCYTIC LEUKEMIA - POSITIVE RESPONSE TO RETINOIC ACID TREATMENT

Authors
CIGUDOSA JC CALASANZ MJ ODERO MD MARIN J BENGOECHEA E GULLON A
Citation
Jc. Cigudosa et al., A VARIANT T(14-17) IN ACUTE PROMYELOCYTIC LEUKEMIA - POSITIVE RESPONSE TO RETINOIC ACID TREATMENT, Cancer genetics and cytogenetics, 80(2), 1995, pp. 160-161
Citations number
10
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
80
Issue
2
Year of publication
1995
Pages
160 - 161
Database
ISI
SICI code
0165-4608(1995)80:2<160:AVTIAP>2.0.ZU;2-H
Abstract
We present a case of acute promyelocytic leukemia (APL) carrying an at ypical translocation involving chromosomes 14 and 17. This translocati on could be considered a variant of the APL-specific t(15;17). Positiv e response to retinoic acid treatment suggests molecular rearrangement of retinoic acid receptor alpha.