MARINE-ALGAE THAT DISPLAY ANTI-TUMORIGENIC ACTIVITY AGAINST AGROBACTERIUM-TUMEFACIENS

Thirty-five extracts representing different seasonal growths of 17 mar ine algal species collected from the Alexandria coast were tested for anti-tumorigenic activity against Agrobacterium tumefaciens galls on p otato discs. Eleven extracts (nine species) displayed > 20% inhibition of tumor initiation, with three of these (Codium tomentosum, winter; Jania rubens, summer; Padina pavonia, winter) displaying relatively hi gh activity. Bacterial viability tests showed that the inhibitory effe cts were directly due to anti-tumorigenesis rather than an indirect re sult of anti-bacterial activity.