In this 5-year prospective study, we determined the feasibility of red
ucing polypharmacy in a long-term care institution by a systematic rev
iew of the pharmacy records, At 6-month intervals, the computer printo
ut of all medications prescribed to patients in a 550-bed institution
was reviewed. After patients taking more than 10 different drugs were
identified, their physician was notified and was asked to review their
medications according to specific guidelines. The number of patients
taking 10 or more medications was reduced from 67, when the program wa
s started, to 9. The average number of medications per patient was red
uced from 5.5 to 4.6. This program reduced the prevalence of polypharm
acy and had longlasting effects on the physicians' prescribing habits.
We also believe it led to improved patient care by reducing the poten
tial for drug interactions and to cost savings for the pharmacy.