In this series, 35 patients with medical renal disease had renal biops
y guided by computed tomography (CT), Biopsies were done by a coaxial
technique in which a thin-walled 16 gauge guide needle is placed adjac
ent to the renal capsule of the lower pole, An 18 gauge cutting needle
is then placed through the guide needle, and multiple samples (2 to 4
) are obtained with an automated biopsy gun, Adequacy of specimens is
immediately checked in the CT suite using low-power microscopy, Specim
ens are submitted for light, electron, and immunofluorescence microsco
py, Adequate tissue for definite diagnosis was obtained in 33 of the 3
5 patients (94%), One patient had moderate postbiopsy bleeding and was
hospitalized, There were no major complications, CT-guided renal biop
sy using a coaxial technique and automated biopsy gun is an effective
means of obtaining tissue for the evaluation of medical rend disease.