Although neither sarcoidosis nor HIV infection is rare, only eight pat
ients with both diseases have been described. None of the eight had sa
rcoid myopathy. We describe a patient who had HIV infection and decrea
sed CD4+ T-lymphocytes as well as sarcoidosis with muscle involvement.
During 3 years of observation, primary sarcoidosis remitted and myopa
thic symptoms were controlled with prednisone. No opportunistic infect
ions occurred during more than 3 years of prednisone therapy.