Lymphomas generally have a good prognosis compared with squamous carci
nomas. The present study investigates a series of 185 lymphomas of the
head and neck seen over a 30-year-period. The records of 236 patients
were examined and the histology slides reviewed. The lymphomas were c
lassified according to the working formulation method and staged using
the Ann Arbor system. A total of 185 patients had a non-Hodgkin's lym
phoma, of those 43 were low grade, nine intermediate and 103 high grad
e. The histology slides of 30 patients were not available for review.
In addition, 51 patients had Hodgkin's disease. One hundred and fifty
patients were stage 1 or 2 and 74 stage 3 or 4. In 12 patients insuffi
cient data was available for staging; 152 were extranodal and 84 nodal
. The 5-year survival of those patients with Hodgkin's disease was 73%
. For the patients with non-Hodgkin's lymphoma the 5-year survival was
43% for low grade and 48% for high grade lesions. The survival of pat
ients with Hodgkin's disease was significantly better than for non-Hod
gkin's lymphoma (P < 0.01). The 5-year survival of patients with extra
nodal disease was 54% and for patients with nodal disease 65% (P = NS)
. Treatment was by irradiation for localized lesions and by chemothera
py or a combination for more advanced lesions. Lymphomas have a relati
vely good prognosis in the head and neck as elsewhere in the body and
every effort should be made to provide adequate diagnosis and treatmen
t in combined clinics.