T. Ariyama et al., ASSIGNMENT OF THE HUMAN PROTEIN-TYROSINE-PHOSPHATASE, RECEPTOR-TYPE, ZETA (PTPRZ) GENE TO CHROMOSOME BAND 7Q31.3, Cytogenetics and cell genetics, 70(1-2), 1995, pp. 52-54
Human protein tyrosine phosphatase, receptor-type, zeta (PTPRZ; also d
enoted HPTP xi or RPTP beta) has a large extracellular region with the
N-terminal carbonic anhydrase-like domain and a cytoplasmic region wi
th two tandemly located protein tyrosine phosphatase domains. One of t
he characteristics of PTPRZ is its preferential expression in the cent
ral nervous system. We localized the human PTPRZ gene to chromosome ba
nd 7q31.3 by somatic cell hybrid mapping and fluorescence in situ hybr
idization.