A MICRODISSECTION LIBRARY OF THE RAT RENAL-CARCINOMA GENE REGION

Citation
Dw. Bell et al., A MICRODISSECTION LIBRARY OF THE RAT RENAL-CARCINOMA GENE REGION, Cytogenetics and cell genetics, 70(1-2), 1995, pp. 92-94
Citations number
11
Categorie Soggetti
Cell Biology","Genetics & Heredity
ISSN journal
03010171
Volume
70
Issue
1-2
Year of publication
1995
Pages
92 - 94
Database
ISI
SICI code
0301-0171(1995)70:1-2<92:AMLOTR>2.0.ZU;2-C
Abstract
Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequ ences in the vicinity of this locus following the microdissection, con struction and characterization of a region-specific DNA library for ra t chromosome band 10q12.