LOCALIZATION OF THE MURINE HOMOLOG OF THE ANAPLASTIC LYMPHOMA KINASE (ALK) GENE ON MOUSE CHROMOSOME-17

Authors
MATHEW P MORRIS SW KANE JR SHURTLEFF SA PASQUINI M JENKINS NA GILBERT DJ COPELAND NG
Citation
P. Mathew et al., LOCALIZATION OF THE MURINE HOMOLOG OF THE ANAPLASTIC LYMPHOMA KINASE (ALK) GENE ON MOUSE CHROMOSOME-17, Cytogenetics and cell genetics, 70(1-2), 1995, pp. 143-144
Citations number
6
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
70
Issue
1-2
Year of publication
1995
Pages
143 - 144
Database
ISI
SICI code
0301-0171(1995)70:1-2<143:LOTMHO>2.0.ZU;2-Y
Abstract
The murine homolog of the human anaplastic lymphoma kinase gene, which encodes a membrane-spanning receptor tyrosine kinase in the insulin r eceptor kinase subfamily, was assigned to mouse Chromosome 17 by inter specific backcross analysis. This assignment further confirms the homo logy between a portion of the distal Chromosome 17 and the short arm o f human chromosome 2 and extends this region in the mouse by an additi onal 3 cM.