SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF DERIVATIVES OF ISOXAZOLO[4,3-D]BYRIMIDINE .3.

Authors
WAGNER E POREBA K JAKOWICZ I BALICKA D RUTKOWSKA M KEDZIERSKAGOZDZIK L SZELAG A
Citation
E. Wagner et al., SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF DERIVATIVES OF ISOXAZOLO[4,3-D]BYRIMIDINE .3., Il Farmaco, 50(3), 1995, pp. 183-187
Citations number
7
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Il Farmaco → ACNP
ISSN journal
0014827X
Volume
50
Issue
3
Year of publication
1995
Pages
183 - 187
Database
ISI
SICI code
0014-827X(1995)50:3<183:SAPPOD>2.0.ZU;2-N
Abstract
Synthesis of new isoxazolo[4,5-d]pyrimidine derivatives is reported. S ome of isoxazolo[4,5-d]pyrimidine derivatives were tested for anticonv ulsant, anxiolytic and antiserotonine activity. Compounds 14 and 16 pr oved active against hypothermia induced by reserpine and hyperthermia induced by m-CPP.