INVESTIGATIONS OF PRIMARY CULTURES OF REN AL-CELL CARCINOMAS (RCC), WITH REGARD TO IMMUNOMODULATORY CAPACITY

Authors
KNOFEL B JUNKER U NUSKE K ELSEWEIFI A JUNKER K KOSMEHL H JAGER L
Citation
B. Knofel et al., INVESTIGATIONS OF PRIMARY CULTURES OF REN AL-CELL CARCINOMAS (RCC), WITH REGARD TO IMMUNOMODULATORY CAPACITY, Immunitat und Infektion, 23(2), 1995, pp. 72-73
Citations number
5
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Immunitat und Infektion → ACNP
ISSN journal
03401162
Volume
23
Issue
2
Year of publication
1995
Pages
72 - 73
Database
ISI
SICI code
0340-1162(1995)23:2<72:IOPCOR>2.0.ZU;2-P
Abstract
The presented results show that renal cell carcinomas (RCC) have parti al immunomodulatory capacity (production of cytokines as IL-6, -10, -1 1; modulation of mitogen-induced transformation of T lymphocytes). The production of IL-10 shows a tendency to correlate with higher staging and grading of RCC. The cytokine production does not correlate with s pecific types of RCC. Direct immunosuppression of T lymphocytes in lym phocyte transformation tests (LTT) was not detectable.