IRON AND LACTOFERRIN IN MILK OF ANEMIC MOTHERS GIVEN IRON SUPPLEMENTS

The factors regulating concentrations of iron and iron-binding protein s in milk are incompletely known. Since anemic women usually are given iron supplements, we have evaluated the effect of this practice on ir on and lactoferrin levels in milk. Lactating Peruvian mothers (n=29) w ere studied during the first month of lactation. Lactoferrin and iron in milk were analyzed at 2 and 30 days post-partum. Mothers who were a nemic (Hgb <110 g/L) (n=19) received iron treatment starting from the second day after delivery. Hemoglobin concentrations improved in the t reated group from a mean of 92 g/L to 105 g/L and hematocrit from 28.2 % to 32.6% (p < 0.05). Iron concentration in milk from anemic mothers was 0.90 and 0.38 mg/L at 2 and 30 days post-partum. In the non-anemic group, iron concentration was 0.80 and 0.35 mg/ml. The concentration of lactoferrin in milk from the anemic group was 6.75 mg/ml and 3.67 m g/ml analyzed at the 2nd and 30th day of lactation, respectively, and for the non-anemic group 5.34 mg/mL and 4.34 mg/ml. Milk iron values w ere within the range previously reported for healthy mothers. Thus, an emia did not affect milk iron or lactoferrin concentrations (day 2). T reatment with iron improved iron status of the anemic women but did no t affect iron or lactoferrin levels in their milk (day 30).