MUSCULAR PAIN-FASCICULATION SYNDROME

We report on four patients in whom muscular pain-fasciculation syndrom e was diagnosed. Clinical characteristics, electrodiagnostic features and muscle biopsy findings in our patients were compatible with polyne uropathy with axonal degeneration. In one case electrophysiological fi ndings indicated an additional alteration of the first motor neuron. T he chronic and mild course differentiates this disorder from other neu romuscular diseases with spontaneous muscle activity. Differential dia gnosis and pathogenesis of this rare syndrome are discussed on the bas is of our case records.