SWAINSONINE PRODUCTION IN FED-BATCH FERMENTATIONS OF METARHIZIUM-ANISOPLIAE

Authors
PATRICK MS ADLARD MW KESHAVARZ T
Citation
Ms. Patrick et al., SWAINSONINE PRODUCTION IN FED-BATCH FERMENTATIONS OF METARHIZIUM-ANISOPLIAE, Biotechnology letters, 17(4), 1995, pp. 433-438
Citations number
12
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
17
Issue
4
Year of publication
1995
Pages
433 - 438
Database
ISI
SICI code
0141-5492(1995)17:4<433:SPIFFO>2.0.ZU;2-5
Abstract
Extended and enhanced production of swainsonine was achieved from fed- batch fermentations of the fungus Metarhizium anisopliae. A complex me dium based on oatmeal extract was intermittently fed with D-glucose an d/or lysine. Swainsonine titres were improved eleven-fold and the dura tion of production extended was from 240 to 550 hours compared with a batch culture under the same conditions.