ACQUIRED LARYNGEAL LESIONS - PATHOLOGICAL-STUDY USING SERIAL MACROSECTIONS

Objective: To present the pathologic findings of acquired lesions of t he larynx in infants. Setting: The Laryngeal Development Laboratory of Children's Memorial Hospital, Chicago, ill. Materials: One hundred fi fteen larynges received at postmortem examination from 1975 to 1992. M ain Outcome Measure: Acquired laryngeal lesions from intubation trauma . Technique: Whole-organ serial section of larynges. Results: Fifty-th ree of the 115 specimens exhibited acquired laryngeal lesions: 36, sub mucosal mucous gland hyperplasia; 12, submucosal fibrosis; 10, granula tion tissue; eight, ulceration; eight, fragmented or distorted cricoid ; four, cricoid ossification; four, ductal cysts; three, healed furrow s, and one, anterior glottic synechia. Some specimens exhibited more t han one type of acquired abnormality.