DIFFUSE LEPTOMENINGEAL GLIOMATOSIS WITH OSTEOBLASTIC METASTASES AND NO EVIDENCE OF INTRAAXIAL LESIONS

An autopsy-proved case of cerebral and medullary leptomeningeal glioma tosis and diffuse osteoblastic metastases without evidence of intraaxi al tumor is described. MR findings included diffuse thickening of the cerebral and medullary leptomeninges on T1-weighted, proton density-we ighted, and T2-weighted images and abnormal enhancement of the sulci a nd cisterns of the cerebrum, brain stem, cerebellum, and medulla on po stcontrast T1-weighted images. MR also showed several areas of replace ment of the normal bone marrow of the skull. No intraaxial lesion was seen.