M. Karamac et R. Amarowicz, INHIBITION OF PANCREATIC LIPASE BY PHENOLIC-ACIDS - EXAMINATION IN-VITRO, Zeitschrift fur Naturforschung. C, A journal of biosciences, 51(11-12), 1996, pp. 903-905
The influence of addition 2, 4, 6, 8, and 10 mu M of benzoic and cinna
mic acids and selected phenolic acids (salicylic, p-hydroxybenzoic, ge
ntisic, protocatechuic, vanillic, syringic, o-coumaric, p-coumaric, ca
ffeic, ferulic, sinapic) on the activity of pancreatic lipase was exam
ined in vitro. The strongest inhibition activities were observed with
caffeic, ferulic and benzoic acid, while sinapic and gentisic acids pr
oduced the lowest inhibition.