THE UNIVERSAL LEUCINE CODON CTG IN THE SECRETED ASPARTYL PROTEINASE-1(SAP1) GENE OF CANDIDA-ALBICANS ENCODES A SERINE IN-VIVO

Authors
WHITE TC ANDREWS LE MALTBY D AGABIAN N
Citation
Tc. White et al., THE UNIVERSAL LEUCINE CODON CTG IN THE SECRETED ASPARTYL PROTEINASE-1(SAP1) GENE OF CANDIDA-ALBICANS ENCODES A SERINE IN-VIVO, Journal of bacteriology, 177(10), 1995, pp. 2953-2955
Citations number
22
Categorie Soggetti
Microbiology
Journal title
Journal of bacteriology → ACNP
ISSN journal
00219193
Volume
177
Issue
10
Year of publication
1995
Pages
2953 - 2955
Database
ISI
SICI code
0021-9193(1995)177:10<2953:TULCCI>2.0.ZU;2-C
Abstract
A number of Candida species possess a tRNA(Ser)-like species that reco gnizes CTG codons that normally specify leucine (Leu) in the universal code of codon usage. Mass spectrometry and Edman sequencing of peptid es from the secreted aspartyl proteinase isoenzyme (Sap1) demonstrate that positions specified by the CTG codon contain a nonmodified serine (Ser) in Candida albicans.