SYNTHESIS OF SOME MULTIAZAHETEROCYCLES AS SUBSTITUENTS TO QUINOLONE MOIETY OF SPECIFIC BIOLOGICAL-ACTIVITY

New Schiff bases, hydrazones and semicarbazones derived from -4-hydrox y-6-methyl-2-oxoquinoline-3-carbaldehyde, have been synthesized. The s emicarbazone was subjected to react with 2,3-dichloroquinoxaline, chlo roacetic acid, and oxalyl chloride affording multiazaheterocycles subs tituted to quinolone moiety at position 3. Condensation of the 2-imida zolidine-thione derivative with some amines and hydrazines yielded som e new heterocyclic systems of expected biological activity. Some of th ese imine derivatives were tested for their bactericidal, fungicidal, and molluscicidal activities. The structures of all new quinolone deri vatives have been characterized by chemical reactions and physical too ls.