GASTROESOPHAGEAL REFLUX LARYNGITIS RESISTANT TO OMEPRAZOLE THERAPY

Gastroesophageal reflux disease (GERD) is known to cause a variety of symptoms that lead a patient to seek otolaryngologic care. New advance s in the treatment of GERD have enabled otolaryngologists to eliminate most of the signs and symptoms caused by acid reflux. Omeprazole, the most recent pharmacologic advancement, has been reported to be univer sally successful in controlling acid release from the stomach of patie nts with GERD. This report describes a series of patients with GERD fo r whom high-dose omeprazole therapy was not successful in completely r educing gastric acid levels of GERD symptomatology.