SYNERGISTIC EFFECT OF PIPERONYL BUTOXIDE ON SOME ZOOCIDES AND INSECT GROWTH-REGULATORS DURING POSTEMBRYONIC DEVELOPMENT AND ADULT LIFE OF FLIES (NEOBELLIERIA-BULLATA, MUSCA-DOMESTICA)

The synergistic effect of a well-known synthetic methylene-dioxyphenyl compound, piperonyl butoxide (PBO) was investigated on some neuroacti ve zoocides and insect growth inhibitors during postembryonic developm ent and adult life of Neobellieria bullata (Dipt., Sarcophagidae) and Musca domestica (Dipt., Muscidae). PBO has proved to be a good synergi st of methoprene and permethrin during the larval development of N. bu llata and has a high synergistic effect on tetramethrin during adult l ife of M. domestica. Activity of diflubenzuron, fenoxycarb, gamma HCH and carbofuran was also increased after PBO coadministration. It was c oncluded that where cyt. P-450 system is involved in the metabolism of zoocides, PBO has high synergistic effect in cases investigated.