A NOVEL SYNTHETIC APPROACH TO CYCLOOCTA-1,5-DIYNES AND CYCLOOCT-3-ENE-1,5-DIYNES VIA COBALT-COMPLEXED PROPARGYL RADICALS

Authors
MELIKYAN GG KHAN MA NICHOLAS KM
Citation
Gg. Melikyan et al., A NOVEL SYNTHETIC APPROACH TO CYCLOOCTA-1,5-DIYNES AND CYCLOOCT-3-ENE-1,5-DIYNES VIA COBALT-COMPLEXED PROPARGYL RADICALS, Organometallics, 14(5), 1995, pp. 2170-2172
Citations number
40
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Organometallics → ACNP
ISSN journal
02767333
Volume
14
Issue
5
Year of publication
1995
Pages
2170 - 2172
Database
ISI
SICI code
0276-7333(1995)14:5<2170:ANSATC>2.0.ZU;2-0
Abstract
A novel synthetic strategy has been elaborated to produce Co-2(CO)(6)- complexed 1,5-cyclooctadiynes and the first cyclooct-3-ene-1,5-diyne d erivative. Eight-membered rings are formed with high dl-diastereoselec tivity (de greater than or equal to 98%) by reduction of the correspon ding propargyl dication complexes under hetero- (Zn) and homogeneous ( Na/Ph(2)CO) conditions. A novel ''red-ox'' decomplexation method has b een developed for 1,5-cyclooctadiynes.