W. Ciesielski et al., APPLICATION OF IODOMETRIC REACTION IN AN ALKALINE-MEDIUM TO DETERMINATION OF 2-MERCAPTO-4(3H)-QUINAZOLINONE, Chemia Analityczna, 41(6), 1996, pp. 1083-1087
A new method for the determination of 2-mercapto-4(3H)-quinazolinone,
using its reaction with iodine in an alkaline medium is presented. Vol
umetric titration in an alkaline medium with tile potentiometric end-p
oint detection enables determination of 50-500 mu mol (8.9-89 mg) of t
he analyte. In coulometric titration with the anodically generated iod
ine, using biamperometric end-point detection, 0.2-2 mu mol (0.036-0.3
6 mg) of 2-mercapto-4(3H)-quinazolinone was successfully determined. I
n both variants the relative standard deviation was below 1%.