APPLICATION OF IODOMETRIC REACTION IN AN ALKALINE-MEDIUM TO DETERMINATION OF 2-MERCAPTO-4(3H)-QUINAZOLINONE

Authors
CIESIELSKI W ZAKRZEWSKI R KASPRZAK K
Citation
W. Ciesielski et al., APPLICATION OF IODOMETRIC REACTION IN AN ALKALINE-MEDIUM TO DETERMINATION OF 2-MERCAPTO-4(3H)-QUINAZOLINONE, Chemia Analityczna, 41(6), 1996, pp. 1083-1087
Citations number
7
Categorie Soggetti
Chemistry Analytical
Journal title
Chemia Analityczna → ACNP
ISSN journal
00092223
Volume
41
Issue
6
Year of publication
1996
Pages
1083 - 1087
Database
ISI
SICI code
0009-2223(1996)41:6<1083:AOIRIA>2.0.ZU;2-2
Abstract
A new method for the determination of 2-mercapto-4(3H)-quinazolinone, using its reaction with iodine in an alkaline medium is presented. Vol umetric titration in an alkaline medium with tile potentiometric end-p oint detection enables determination of 50-500 mu mol (8.9-89 mg) of t he analyte. In coulometric titration with the anodically generated iod ine, using biamperometric end-point detection, 0.2-2 mu mol (0.036-0.3 6 mg) of 2-mercapto-4(3H)-quinazolinone was successfully determined. I n both variants the relative standard deviation was below 1%.