STRUCTURE AND CONFORMATIONAL FEATURES OF TETRAHYDROTHIENOTHIEPINOISOXAZOLE AS A NOVEL HETEROCYCLIC SYSTEM

Authors
KRAYUSHKIN MM VORONTSOVA LG KURELLA MG KALIK MA ZVEZDINA EY
Citation
Mm. Krayushkin et al., STRUCTURE AND CONFORMATIONAL FEATURES OF TETRAHYDROTHIENOTHIEPINOISOXAZOLE AS A NOVEL HETEROCYCLIC SYSTEM, Russian chemical bulletin, 43(10), 1994, pp. 1700-1702
Citations number
6
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
43
Issue
10
Year of publication
1994
Pages
1700 - 1702
Database
ISI
SICI code
1066-5285(1994)43:10<1700:SACFOT>2.0.ZU;2-O
Abstract
The crystal and molecular structure of a novel heterocyclic system, et rahydrothieno[3',2:6,7]thiepino[4,5-c]isoxazole, has been determined b y X-ray analysis. The seven-membered ring has the boat conformation (B ), while the isoxazoline cycle has the flat chair conformation ((3)E). There are strong steric strains between the vicinal protons at the C( 3a), C(3), and C(4) atoms.