This study assessed the relationship of depression, anxiety, and hosti
lity to physical health in a multicultural student population (N = 106
). When controlling for a variety of demographic and health risk facto
rs (viz., age, sex, body mass, smoking, alcohol, salt, caffeine, and e
xercise), hostility, depression, and anxiety were related to higher re
ported incidences of physical symptoms and somatic illness. Depression
and hostility had the strongest relationships with physical health, a
lthough the most striking single relationship was between depression a
nd illness. Results suggest that it may be premature to focus our atte
ntion on hostility in research on the personality-illness relationship
. They also suggest that the health behavior model of the relationship
between personality and disease does not provide an adequate explanat
ion, since negative affect was significantly associated with illness e
ven when controlling for a variety of health risk factors.