This study evaluates the frequency and significance of thrombus format
ion on the surface of intravascular ultrasound (US) imaging catheters.
The investigation includes 63 consecutive patients who underwent 32 a
rterial and 38 venous intravascular procedures. At the end of the imag
ing procedure the US findings were observed during withdrawal of the c
atheter into the introducer sheath. Thrombus formation was demonstrate
d in 5 (7%). The largest thrombus fragments had a cross-sectional dime
nsion of 2.2X1.0 mm. There was a significant correlation between the i
ncidence of thrombus formation and the occurrence of malign neoplastic
disease. No relation was found between the frequency of thrombus form
ation and the duration of the imaging procedure or the type of US cath
eter, It is concluded that the thrombogenicity of intravascular US ima
ging devices is not higher than that of conventional angiographic cath
eters. The observed ''pull-out'' thrombi were small and it is unlikely
that they could have any clinical significance.