INTERSPECIFIC COMPLEMENTATION BETWEEN MOUSE AND CHINESE-HAMSTER CELL MUTANTS HYPERSENSITIVE TO IONIZING-RADIATION

Authors
SATO K CHEN DJ EGUCHIKASAI K ITSUKAICHI H ODAKA T STRNISTE GF
Citation
K. Sato et al., INTERSPECIFIC COMPLEMENTATION BETWEEN MOUSE AND CHINESE-HAMSTER CELL MUTANTS HYPERSENSITIVE TO IONIZING-RADIATION, Journal of radiation research, 36(1), 1995, pp. 38-45
Citations number
23
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
Journal of radiation research → ACNP
ISSN journal
04493060
Volume
36
Issue
1
Year of publication
1995
Pages
38 - 45
Database
ISI
SICI code
0449-3060(1995)36:1<38:ICBMAC>2.0.ZU;2-Q
Abstract
Interspecific and intraspecific hybrids were formed between mouse and Chinese hamster cell mutants hypersensitive to ionizing radiation and their radiosensitivities were examined. Chinese hamster cell mutants i rs1, irs2 and irs3 and mouse mammary carcinoma cell mutants SX9 and SX 10 have been found to belong to five different complementation groups. A radiosensitive mouse lymphoma cell line L5178Y-S has been demonstra ted to be different from the X-ray sensitive mouse cell mutants M10 an d LX830, both of which are derived from L5178Y cells, in their complem entation groups. L5178Y-S is also distinct from SX9 and SX10.