IS THE RELATIONSHIP BETWEEN SUPINE BLOOD-PRESSURE AND POSTURAL CHANGES IN BLOOD-PRESSURE ARTIFACTUAL - RESULTS FROM THE KUOPIO ISCHEMIC-HEART-DISEASE RISK FACTOR STUDY

Objective: To investigate whether there is an association between init ial supine blood pressure and postural changes in blood pressure (stan ding minus supine blood pressure). Methods: Using data from the Kuopio (Finland) Ischemic Heart Disease Risk Factor Study (KIHD), we simulat ed the problem and found the suggested solution based on the work of B lomqvist. We then applied the Blomqvist correction to the KIHD data wi th real measurement errors. Results: The observed regression slope was substantially reduced, indicating that there is no relationship betwe en the initial blood pressure and the postural change in blood pressur e. Conclusion: Only the broad application of the method of Blomqvist t o other data sets will determine the generalizability of the present f inding that initial blood pressure is unrelated to the postural change in blood pressure.