DESIGN OF EXPERIMENTS FOR THE DETERMINATION OF THE DETECTION LIMIT INCHEMICAL-ANALYSIS

Authors
KUSELMAN I SHENHAR A
Citation
I. Kuselman et A. Shenhar, DESIGN OF EXPERIMENTS FOR THE DETERMINATION OF THE DETECTION LIMIT INCHEMICAL-ANALYSIS, Analytica chimica acta, 306(2-3), 1995, pp. 301-305
Citations number
13
Categorie Soggetti
Chemistry Analytical
Journal title
Analytica chimica acta → ACNP
ISSN journal
00032670
Volume
306
Issue
2-3
Year of publication
1995
Pages
301 - 305
Database
ISI
SICI code
0003-2670(1995)306:2-3<301:DOEFTD>2.0.ZU;2-P
Abstract
The uncertainty of values of the detection limit in chemical analysis is described considering the reasonable risk of false analyte detectio n and false nondetection, the number of analytical results and some ot her parameters of the experimental design. Calculations have been made of minimum number of certified reference materials or standard soluti ons and number of replicates needed to design the experiments for dete rmination of detection limit based on calibration data.