H-1 AND C-13 NMR-STUDY OF THE MOLECULAR INTERACTION MECHANISM BETWEENCHLORAMPHENICOL AND HUMAN SERUM-ALBUMIN

Authors
PANOV V SHIPANOVA I MICHTCHENKO A SHABUNIN I SHIMANOVSKII N SIBELDINA L SERGEEV P
Citation
V. Panov et al., H-1 AND C-13 NMR-STUDY OF THE MOLECULAR INTERACTION MECHANISM BETWEENCHLORAMPHENICOL AND HUMAN SERUM-ALBUMIN, Biochemistry and molecular biology international, 35(2), 1995, pp. 457-460
Citations number
7
Categorie Soggetti
Biology
Journal title
Biochemistry and molecular biology international → ACNP
ISSN journal
10399712
Volume
35
Issue
2
Year of publication
1995
Pages
457 - 460
Database
ISI
SICI code
1039-9712(1995)35:2<457:HACNOT>2.0.ZU;2-W
Abstract
Molecular mechanism of the interaction between human serum albumin and cloramphenicol was studied by H-1 and C-13 NMR-spectroscopy. It was f ound that the main role belongs to [GRAPHICS] groups of chloramphenico l. A schematic model of the complex-formation between serum albumin an d chloramphenicol was proposed.