CHIRAL 2-CYANO ESTERS AS SYNTHETIC INTERMEDIATES IN THE SYNTHESIS OF R-ALPHA-METHYLVALINE AND S-ALPHA-METHYLVALINE

Authors
CATIVIELA C DIAZDEVILLEGAS MD GALVEZ JA LAPENA Y
Citation
C. Cativiela et al., CHIRAL 2-CYANO ESTERS AS SYNTHETIC INTERMEDIATES IN THE SYNTHESIS OF R-ALPHA-METHYLVALINE AND S-ALPHA-METHYLVALINE, Tetrahedron, 51(20), 1995, pp. 5921-5928
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
20
Year of publication
1995
Pages
5921 - 5928
Database
ISI
SICI code
0040-4020(1995)51:20<5921:C2EASI>2.0.ZU;2-I
Abstract
A divergent stereoselective synthesis of R and S alpha-methylvaline fr om (2RS) (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-cyano-3-methyl butanoate has been developed.