THE FUSION OF TEL AND ABL IN HUMAN ACUTE LYMPHOBLASTIC-LEUKEMIA IS A RARE EVENT

Authors
JANSSEN JWG RIDGE SA PAPADOPOULOS P COTTER F LUDWIG WD FONATSCH C RIEDER H OSTERTAG W BARTRAM CR WIEDEMANN LM
Citation
Jwg. Janssen et al., THE FUSION OF TEL AND ABL IN HUMAN ACUTE LYMPHOBLASTIC-LEUKEMIA IS A RARE EVENT, British Journal of Haematology, 90(1), 1995, pp. 222-224
Citations number
12
Categorie Soggetti
Hematology
Journal title
British Journal of Haematology → ACNP
ISSN journal
00071048
Volume
90
Issue
1
Year of publication
1995
Pages
222 - 224
Database
ISI
SICI code
0007-1048(1995)90:1<222:TFOTAA>2.0.ZU;2-2
Abstract
We have recently identified a common ALL patient which harboured a chr omosomal fusion between the TEL gene on chromosome 12 and the ABL gene on chromosome 9. We designed an RT-PCR assay to screen 186 adult ALL and 30 childhood ALL patients for this novel translocation. We were un able to identify any additional cases with a TEL/ABL fusion product.