The National Institute of Mental Health joint study by the United Stat
es and Israel, known as the Israeli High-Risk Study, is a unique long-
term followup investigation of children at genetic risk for schizophre
nia. We compared the development of psychiatric disorder in two groups
of such children, one group raised in kibbutz environments, the other
by their own parents. Matched controls were studied as well. The subj
ects were evaluated at ages 11, 17, and 26; an extensive battery of co
gnitive and clinical tests, as well as psychophysiological and diagnos
tic procedures, was used. This issue of the Schizophrenia Bulletin rep
orts and summarizes evaluations conducted when the subjects were in th
eir early thirties, as well as some previously unreported data obtaine
d when the subjects were 17 years old.