REANALYSIS OF SCOR AND ANXIETY MEASURES IN THE ISRAELI HIGH-RISK STUDY

In an earlier study, skin conductance orienting response (SCOR) and an xiety measures obtained when the subjects of the Israeli High-Risk Stu dy were 11 years old were analyzed, using adult diagnostic information , when the subjects were 26 years old. The present study considers sim ilar data obtained from most of this sample when the subjects were 16 years old. As in the earlier analysis, those subjects who would receiv e a schizophrenia spectrum diagnosis at 26 had higher anxiety ratings at age 16. Nondiagnosed index subjects also had significantly higher a nxiety ratings than the nondiagnosed controls. The subjects who would receive affective spectrum diagnoses at age 26 had the most hyporespon sive SCORs, as predicted, while the subjects who would later be diagno sed in the schizophrenia spectrum had an unexpected hyperresponsive SC OR to the dishabituation tone in a habituation series. Further conside ration of the long-term stability of SCORs seems necessary; they may b e related to the developing psychopathological processes.