Dj. Dodson et al., PREVALENCE OF HYPERCHOLESTEROLEMIA AND CORONARY HEART-DISEASE RISK-FACTORS AMONG SOUTHEAST-ASIAN REFUGEES IN A PRIMARY-CARE CLINIC, Journal of clinical pharmacy and therapeutics, 20(2), 1995, pp. 83-89
The National Cholesterol Education Program's guidelines for the detect
ion, evaluation, and treatment of high serum cholesterol in adults wer
e employed in screening 155 Southeast Asian refugees in a primary care
clinic in Seattle, Washington. In order to determine the need for a t
herapeutic intervention, information also was collected on the presenc
e of other coronary heart disease (CHD) risk factors. Male gender (39%
), cigarette smoking (27%) and hypertension (26%) were the most common
CHD risk factors; diabetes mellitus, obesity, a family or prior histo
ry of CHD or eerebral/peripheral vascular disease were each noted in l
ess than 10%. The mean serum total cholesterol was 194 mg/dl. Thirty-s
even (24%) patients required further lipoprotein analysis based on cho
lesterol level, history of CHD and risk factors for CHD. Twenty-one (6
6%) of 32 patients who underwent lipoprotein analysis (14% of all pati
ents) were candidates for a therapeutic intervention for hypercholeste
rolaemia. Additionally, 14 (44%) patients undergoing lipoprotein analy
sis had depressed high-density lipoprotein levels (<35 mg/dl). We conc
lude that CHD risk factors including hypercholesterolaemia are common
in Southeast Asian refugee clinic patients and that in many, a therape
utic intervention may well be justified. Southeast Asian refugees shou
ld be routinely screened for hypercholesterolaemia and other CHD risk
factors in accordance with the National Cholesterol Education Program'
s guidelines.