POLAR STEROIDS FROM THE SPONGES TRACHYOPSIS-HALICHONDROIDES AND CYMBASTELA-CORALLIOPHILA

Authors
MAKARIEVA TN STONIK VA DMITRENOK AS KRASOKHIN VB SVETASHEV VI VYSOTSKII MV
Citation
Tn. Makarieva et al., POLAR STEROIDS FROM THE SPONGES TRACHYOPSIS-HALICHONDROIDES AND CYMBASTELA-CORALLIOPHILA, Steroids, 60(4), 1995, pp. 316-320
Citations number
19
Categorie Soggetti
Biology,"Endocrynology & Metabolism
Journal title
Steroids → ACNP
ISSN journal
0039128X
Volume
60
Issue
4
Year of publication
1995
Pages
316 - 320
Database
ISI
SICI code
0039-128X(1995)60:4<316:PSFTST>2.0.ZU;2-5
Abstract
Fractions of trisulfated trihydroxysteroids from the sponges Trachyops is halichondroides (two different collections) and Cymbastela corallio phila have been isolated and investigated. Ten triacetates were obtain ed from these fractions by desulfatation/acetylation followed by chrom atographic separation, and their structures have been established. Fou r of these derivatives-namely, trincetates of 5 alpha-pregnane-2 beta, 3 alpha,6 alpha-triol (3c), 23,24-dinor-5 alpha-cholane-2 beta,3 alpha ,6 alpha-triol (4c), 5 alpha-cholest-22-ene-2 beta,3 alpha,6 alpha-tri ol (7c), and 24-isopropyl-5 alpha-cholestane-2 beta,3 alpha,6 alpha-tr iol (11c)-are described as new derivatives of natural steroids.