A retrospective study of 46 horses with retropharyngeal lymph node (RP
LN) infection presented to the Rural Veterinary Centre between 1977 an
d 1992 was undertaken. Horses aged less than one year were most common
ly represented (46%). Thirty-nine percent of cases had been exposed to
horses with confirmed or suspected strangles (Streptococcus equi subs
p equi infection) within the previous 8 weeks. Most frequent signs wer
e unilateral or bilateral swelling of the throat region (65%), respira
tory stertor/dyspnoea (35%), purulent nasal discharge (20%), inappeten
ce and signs of depression (15%), and dysphagia (9%). All horses had a
soft tissue density in the retropharyngeal region on radiographs. Rhi
nopharyngoscopy, ultrasonography, haematology as well as cytological a
nd microbial analysis of material aspirated from the soft tissue swell
ing facilitated diagnosis in some horses. Fifteen horses (33%) were tr
eated with procaine penicillin intramuscularly for 4 to 7 days followe
d by oral trimethoprim-sulphadimidine for 7 to 14 days. Non-steroidal
antiinflammatory drugs were administered to 6 horses. Four required tr
acheostomy for severe respiratory distress. The 15 horses treated medi
cally responded to treatment and were discharged from hospital. Three
horses (6%) with mild signs received no treatment and recovered uneven
tfully. Twenty-eight horses (61%) underwent general anaesthesia and su
rgical drainage of a RPLN abscess. Nineteen received procaine penicill
in G for 4 to 7 days. Four of the nine horses that did not receive ant
ibiotic treatment after surgery required further surgical drainage 10
days to 7 weeks after the initial surgery. Limited follow-up informati
on was available for 37 horses. Thirty-two horses were considered to h
ave made complete recovery, 3 horses had died through misadventure and
2 had been euthanased because of chronic ill-thrift.