INTERPRETATION OF MAGNETIZATION-TRANSFER AND PROTON CROSS-RELAXATION SPECTRA OF BIOLOGICAL TISSUES

Magnetization-tfansfer (MT) experiments have been performed at 300 MHz on agar gels, solutions of sodium alginate, bovine nasal cartilage, a nd postmortem porcine muscle, The experimental results elucidate MT me chanisms between mobile macromolecules (correlation time tau(C) On the order of 10(-8) s) and water, and demonstrate the need to incorporate their effects in the characterization of biological samples. In addit ion, the results obtained confirm a recently published three-spin-bath theoretical treatment for proton magnetization transfer. (C) 1995 Aca demic Press, lnc.