EFFECT OF AN ACIDIC ENVIRONMENT ON THE SUSCEPTIBILITY OF HELICOBACTER-PYLORI TO TROSPECTOMYCIN AND OTHER ANTIMICROBIAL AGENTS

Authors
DEBETSOSSENKOPP YJ NAMAVAR F MACLAREN DM
Citation
Yj. Debetsossenkopp et al., EFFECT OF AN ACIDIC ENVIRONMENT ON THE SUSCEPTIBILITY OF HELICOBACTER-PYLORI TO TROSPECTOMYCIN AND OTHER ANTIMICROBIAL AGENTS, European journal of clinical microbiology & infectious diseases, 14(4), 1995, pp. 353-355
Citations number
15
Categorie Soggetti
Immunology,Microbiology
Journal title
European journal of clinical microbiology & infectious diseases → ACNP
ISSN journal
09349723
Volume
14
Issue
4
Year of publication
1995
Pages
353 - 355
Database
ISI
SICI code
0934-9723(1995)14:4<353:EOAAEO>2.0.ZU;2-H
Abstract
The susceptibility of 30 clinical isolates of Helicobacter pylori to t rospectomycin, ampicillin, metronidazole, clarithromycin, azithromycin and clindamycin under varying pH conditions was evaluated. An acidic environment was shown to affect unfavourably the activity of all the a ntimicrobial agents tested. This pH effect was most marked for the two macrolides and for clindamycin.