Joseph Babinski pioneered development of French neurosurgery and world
clinical neurology. Although he was best known for his discovery of t
he extensor plantar response, his foundations in the modern semiology
of neurology are unequivocal. He introduced the concepts and terminolo
gy of cerebellar symptoms and discovered a reflex asymmetry as the sig
n of organic disease. Although he considered the development of French
neurosurgery by his pupils as his greatest accomplishment, it is 'the
sign' that has dominated his legacy over the years. This sign will al
so celebrate a centenary in 1996.