Functional activations of the human brain cortex were observed with a
standard 1.5-tesla MR imaging system using a long time echo fast low-a
ngle shot sequence. Neural activation increases regional cerebral bloo
d flow resulting in increased capillaries and venous blood oxygenation
. Processing requires adapted algorithms because the time course of in
tensity signal showed fluctuations of the baseline. The use of a 'foll
ow-up' method to generate activation maps is proposed. Brain activatio
n was detected in striate cortex during photic stimulation and in sens
orimotor areas while subjects were moving their hands. In mental image
ry tasks, we observed a primary and secondary visual cortex activation
during memory recall of the flashing light. Motor ideation showed an
activation of the rolandic areas.