Objectives: To identify factors associated with a high risk of diabeti
c retinopathy in order to rank patients for urgency of examination by
fundal photography. Design: Retrospective case survey. Patients: Eight
hundred and eighty-eight consecutive diabetic patients who were routi
nely referred for mydriatic fundal photography to the Queen Elizabeth
Hospital, Adelaide, between August 1987 and May 1992. Outcome measures
: The prevalence of non-proliferative and proliferative diabetic retin
opathy, and patient biochemical and demographic characteristics and ur
inary albumin excretion rate. Results: The prevalences of nonprolifera
tive and proliferative diabetic retinopathy were 18.1% and 2.4%, respe
ctively. Multiple logistic regression analysis established that treatm
ent with insulin or oral hypoglycaemic drugs was associated with the h
ighest risk of diabetic retinopathy (odds ratio [OR], 14.7; 95% confid
ence interval [CI], 3.4-63.2), while duration of diabetes greater than
or equal to 7 years (OR, 3.6; 95% CI, 1.9-6.8), age 50-66 years (OR,
2.1; 95% CI, 1.1-4.0) and albumin excretion rate greater than or equal
to 21 mu g/min (OR, 2.2; 95% CI, 1.1-4.5) were also significant risk
factors. Non-significant variables were hypertension, obesity and sex.
Conclusions: Diabetic patients may be ranked for urgency of retinal p
hotographic screening based on mode of treatment and duration of diabe
tes, thereby facilitating examination of patients at highest risk of a
symptomatic diabetic retinopathy and increasing the efficiency of the
screening program.