SYNTHESIS OF A NEW OPTICALLY-ACTIVE TRIPH OSPHINE WITH A NEOPENTANE BACKBONE

Authors
HEIDEL H HUTTNER G ZSOLNAI L
Citation
H. Heidel et al., SYNTHESIS OF A NEW OPTICALLY-ACTIVE TRIPH OSPHINE WITH A NEOPENTANE BACKBONE, Zeitschrift fur Naturforschung. B, A journal of chemical sciences, 50(5), 1995, pp. 729-734
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Zeitschrift fur Naturforschung. B, A journal of chemical sciences → ACNP
ISSN journal
09320776
Volume
50
Issue
5
Year of publication
1995
Pages
729 - 734
Database
ISI
SICI code
0932-0776(1995)50:5<729:SOANOT>2.0.ZU;2-I
Abstract
The resolution of the racemate (BzlOCH(2)) (Me)C(COOH)(COOEt) (+/-)1 i s the entry point for the enantioselective synthesis of the key compou nd 7 (MeC(CH2Cl)(CH2Br) (CH(2)OTfl)). Successive phosphination of 7 fu rnishes the triphosphine 10 eC(CH(2)PPh(2))(CH2DBP)(CH2P(3,5-Me(2)C(6) H(3))(2) in both enantiomeric forms (DBP = dibenzophospholyl). The str uctures of the precursors (+)8S (MeC(CH(2)PPh(2))(CH2DBP)(CH2Cl)) and (+/-)9 (MeC(CH2Br)(CH2Cl)(CH2DBP)) have been confirmed by X-ray analys is.