NEOPLASIA

The incidence of neoplasia in children with HIV infection is currently significantly lower than in adults but almost certain to rise in the future. Over 60 cases of pediatric HIV-associated neoplasia have alrea dy been reported, and it is evident that there is a markedly increased incidence of B cell non-Hodgkin's lymphoma, Kaposi's sarcoma, and lei omyosarcoma. A complex interaction of factors may predispose the AIDS patient to develop malignancies. Although AIDS is still incurable, man y years of survival are possible, and the diagnosis of AIDS should not necessarily preclude appropriate treatment for malignancy.